Can someone explain the reason (mechanism) that MK677 causes muscle pumps/fullness? I understand its impact on recovery, skin, even sleep given the increases in GH and IGF1, but I don't understand why the muscle fullness. I'd love to learn if anyone here knows a bit of (bro)science behind it
Increasing your levels of GH raises the concentration of glucose and free fatty acids. It also stimulates production of IGF-1. Either one of these things are going to give you much more fullness and bigger pumps. Getting more glucose uptake into the muscles, and the power of high levels of IGF-1 will give you some pretty insane pumps and you'll have a lot of fullness because of the super saturation of glucose into the muscles and intra cellular water to make the muscles bigger