A topic I wanted to start some discussion on, is that of Myostatin, and it's role in limiting and even halting gains made on cycle when levels of myostatin reaches high levels in the body.
It's pretty common knowledge that during a cycle, you won't just keep gaining and gaining forever. At some point, your gains will stall out completely despite running the same doses. Myostatin is an unavoidable reality. It is going to happen. For most people, this seems to happen around the 8 week (day 56) mark of a cycle. There are other things that can impact this, like the compounds and doses used. For example, running a heavy cycle with multiple short/no ester compounds at higher doses will raise myostatin much quicker than a lower dosed one or two mild compound cycle with longer esters. However, no matter what myostatin will eventually take over in both cases at some point and stall your gains.
So, what can you do about it to make the most of your cycle? There are myostatin reducers and inhibitors out there, but NONE of them have ever been shown to do anything except empty your wallet unfortunately. Luckily, there are a few tricks to enable you to get a little more out of everything.
Tapering Doses up: if you start at a certain dose and raise the dose slightly every couple weeks or so, this can help overcome myostatin from stalling you out by raising the dose just enough to continue some gains. It won't be a substantial amount, but enough to still make progress. Another tactic is to just increase the dose at or near the 8 week mark just before the gains start to diminish
Adding in a more anabolic compound is another option. For example, someone running a test cycle with EQ might decide at the 8 week mark to add in Tren Ace for this reason. The powerful nature of Tren could continue the gains for a bit longer until myostatin wins once again. Orals could work in this instance as well, but the basic idea is to add in something powerful just before your gains stall.
To lower myostatin, basically you need to lower your doses, come off, or cruise for long enough for it to baseline to normal levels. The amount of time this takes depends on a few things but a good general rule of thumb is to take a good 10-12 weeks cruising or off cycle after being on high levels in order to bring your myostatin down enough to get the most out of your next cycle. If you don't take enough time off before going on high doses, your myostatin will peak out even quicker, and your gains will be much less than what you could have gained.
This is a very interesting and debatable topic, that I love to research and find out what I can on the topic. Please feel free to discuss and share your own views on the subject!
It's pretty common knowledge that during a cycle, you won't just keep gaining and gaining forever. At some point, your gains will stall out completely despite running the same doses. Myostatin is an unavoidable reality. It is going to happen. For most people, this seems to happen around the 8 week (day 56) mark of a cycle. There are other things that can impact this, like the compounds and doses used. For example, running a heavy cycle with multiple short/no ester compounds at higher doses will raise myostatin much quicker than a lower dosed one or two mild compound cycle with longer esters. However, no matter what myostatin will eventually take over in both cases at some point and stall your gains.
So, what can you do about it to make the most of your cycle? There are myostatin reducers and inhibitors out there, but NONE of them have ever been shown to do anything except empty your wallet unfortunately. Luckily, there are a few tricks to enable you to get a little more out of everything.
Tapering Doses up: if you start at a certain dose and raise the dose slightly every couple weeks or so, this can help overcome myostatin from stalling you out by raising the dose just enough to continue some gains. It won't be a substantial amount, but enough to still make progress. Another tactic is to just increase the dose at or near the 8 week mark just before the gains start to diminish
Adding in a more anabolic compound is another option. For example, someone running a test cycle with EQ might decide at the 8 week mark to add in Tren Ace for this reason. The powerful nature of Tren could continue the gains for a bit longer until myostatin wins once again. Orals could work in this instance as well, but the basic idea is to add in something powerful just before your gains stall.
To lower myostatin, basically you need to lower your doses, come off, or cruise for long enough for it to baseline to normal levels. The amount of time this takes depends on a few things but a good general rule of thumb is to take a good 10-12 weeks cruising or off cycle after being on high levels in order to bring your myostatin down enough to get the most out of your next cycle. If you don't take enough time off before going on high doses, your myostatin will peak out even quicker, and your gains will be much less than what you could have gained.
This is a very interesting and debatable topic, that I love to research and find out what I can on the topic. Please feel free to discuss and share your own views on the subject!