I bet DRB has some knowledge on this. I tripped over an article one night that was a "myth buster" type piece. They were arguing in their work that in fact location does matter and when you pin an area it gets more of the effect. That does and doesn't make sense to me because the oil disburses the chemical into the fatty tissue right and then it works into the system from there right??
I have just grown weary of the glute contortion so I use quads and delts more than anywhere else. I am right handed so the right glute is ok... left glute is a pain to hit the spot, but once in I can dispense it without a problem. I pinned too close to a nerve in my left quad once. My dang leg was painful for about 8 or 10 days but it passed. I was worried the first day I was getting an abscess but after reading a lot I realized I had just gotten lazy and pinned too low.