Follow along with the video below to see how to install our site as a web app on your home screen.
Note: This feature may not be available in some browsers.
CB100 said:Going to start my first SARM cycle and looking for some advice on a PCT after. I'm going to run lgd-4033 for 8 weeks. I know this SARM is known for suppression so what would be an ideal pct.
Sent from my iPhone using Tapatalk
DylanGemelli said:i always like to incorporate gw-501516 into any pct i run as well at 20 mg day
StrongerFaster said:DylanGemelli said:i always like to incorporate gw-501516 into any pct i run as well at 20 mg day
What is the basis for running a PPAR-D receptor agonist as a part of PCT?
RickRock said:GW–50156 regulates fat burning through a number of widespread mechanisms; it increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization This shift changes the body’s metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. GW–501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW–501516 may have a protective effect against obesity.
In other (very simplistic) words, GW 501516 causes the body to burn fat more, rather than burning carbohydrates or proteins. This keeps blood sugar more regular and prevents the body from breaking down muscle for energy. This makes exercise more effective, increasing the ability of athletes to cut body fat, build muscle mass, and increase endurance.
From what I have read, during PCT the body goes into a very catabolic state. GW helps prevent the loss of muscle by promoting fat oxidization over catabolism.StrongerFaster said:RickRock said:GW–50156 regulates fat burning through a number of widespread mechanisms; it increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization This shift changes the body’s metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. GW–501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW–501516 may have a protective effect against obesity.
In other (very simplistic) words, GW 501516 causes the body to burn fat more, rather than burning carbohydrates or proteins. This keeps blood sugar more regular and prevents the body from breaking down muscle for energy. This makes exercise more effective, increasing the ability of athletes to cut body fat, build muscle mass, and increase endurance.
Yes, that is what GW does, and I have run it before---but what you pasted doesn't explain the rational specifically for PCT. It has no effect on HPTA or steroid hormone secretion.
Don't get me wrong, not trying to be antagonistic, just trying to learn. IMO I have an excellent grasp on nutrition, supplements, and peptides, intermediate on SARMS, and very novice on AAS. Always willing to learn more, hence the reason I'm here.
StrongerFaster said:RickRock said:GW–50156 regulates fat burning through a number of widespread mechanisms; it increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization This shift changes the body’s metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. GW–501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW–501516 may have a protective effect against obesity.
In other (very simplistic) words, GW 501516 causes the body to burn fat more, rather than burning carbohydrates or proteins. This keeps blood sugar more regular and prevents the body from breaking down muscle for energy. This makes exercise more effective, increasing the ability of athletes to cut body fat, build muscle mass, and increase endurance.
Yes, that is what GW does, and I have run it before---but what you pasted doesn't explain the rational specifically for PCT. It has no effect on HPTA or steroid hormone secretion.
Don't get me wrong, not trying to be antagonistic, just trying to learn. IMO I have an excellent grasp on nutrition, supplements, and peptides, intermediate on SARMS, and very novice on AAS. Always willing to learn more, hence the reason I'm here.
RickRock said:I think you are mistaking what it's purpose is for in post cycle therapy. It is not put in PCT for HPTA purposes in any way, shape, or form.GW is not a hormonal product. It is used specifically for its nutrient partitioning abilities, and anticatabolic effects (muscle sparing) while in a very catabolic state of low hormone levels. This is basically what it is saying in what I posted above. It allows you to burn fat for energy instead breaking down muscle or protein and carbs which your body will need post cycle more than any time to preserve the muscle mass accumulated on cycle.
StrongerFaster said:RickRock said:I think you are mistaking what it's purpose is for in post cycle therapy. It is not put in PCT for HPTA purposes in any way, shape, or form.GW is not a hormonal product. It is used specifically for its nutrient partitioning abilities, and anticatabolic effects (muscle sparing) while in a very catabolic state of low hormone levels. This is basically what it is saying in what I posted above. It allows you to burn fat for energy instead breaking down muscle or protein and carbs which your body will need post cycle more than any time to preserve the muscle mass accumulated on cycle.
Appreciate the clarification Rick, thank you.
HHHTheGame said:What about using Nolva or Torem instead? The only reason I ask is because I have a whole ton of 10mg tabs at home already. I'm going to post the PCT I have laid out in another post so as not to hijack this one.
Thanks,
HHH