you definitely do not go 5 on 2 off with mk677... keep it at 25mg per day, 7 days a week.. do not go any higher than that... the hunger should subside but other than that, side effects are minimal to none... the water retention due to lack of potassium is really the only other side to be worried about and its easily controlled.. other than that, keep dosing steady... if you have any further questions just let me know...