Welp, not sure how many ppl here remember my ed issue and prolactin was the only thing that was consistently slightly out of range around 15-17 ng. Rick and chelades commented the most in my thread. I've tried a few different herbal supps like maca, pruriens, tongkat ali the past few months but nothin really changing. I got the dostinex and now that I got it, i'm scared to use it lol. I'm assuming I would just try .25 e3d, but for how long since I'm not using it with a cycle?
Dostinex (Caber) Facts: By RickRock
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noone can tell you exactly how long brother... you have to get bloodwork to determine that but you have NOTHING to be scared of... the only thing you should be "worried" about is the elevated prolactin.. your FINE bro... you can start moderate at .25 and assess... your all good, don't overthink
your means .5 mg two times per week with 3 days space between ?
That is correct. 0.5mg every three days
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Start with bloodwork buddy. That will tell you how to proceed from there.
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Hi all, just a quick question about dosage when running low dose tren cycles i.e. 300mg per week. I am not running the cycle yet but going through the planning and learning stages. The other compounds and my stats I will discuss on a full write up. In the videos Dylan's talks about .25 to .5 mg e3d. It there a guideline as to where in this range you should be for certain dosages of tren. Or should one stay safe and always go for .5 e3d?
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Just like with an AI, it depends on the individual. People have different sensitivities to prolactin just as they do estrogen. No doses are set in stone. You have to find your dose through trial and error and bloodwork, but generally I'd say 300mg and up I'd run 0.5mg E3D
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You should be using gw anytime you run tren
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Thought as much. Gw was always in the plan as well. Thanks for the advice
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My pleasure to help brother. Anytime
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I started taking half a pill every 3-4 days, and i'm on my third one, about a week and a half in. My sleep hasn't been too great the past week, usually get around 8 hours, but only been getting 5-6 on average, and I get soooooo tired if I'm just sitting for awhile it's ridiculous. I'll literally start to doze and wake up, thinking ok i'm not gonna do it again, and close my eyes for a split second and I go right back into it. Feels crazy to me because I'm always able to control it unless i'm lacking sleep like 2-3 hours a night for a couple days. Seems to be the only side I feel though, which is good! Can't imagine what i'd feel like if I took a full .5 dose.
thats common bro... its a normal side effect with the lethargy...
Are there any worries if prolactin gets to low? I know if estrogen gets low it could cause issues but what if prolactin gets really low?
It could be enough more than likely, but everybody is a little different. Some need more and some need less
You are talking about a minimal impact on prolactin levels, and yes to some degree it is true that estrogen and aromatization is needed to produce prolactin, but some people than are more estrogen and prolactin prone are always going to need an anti prolactin no matter what
[h=1]Low Prolactin[/h]Many men are under the belief that low prolactin is a good thing and will help them in the bedroom. This comes from several studies on different subpopulations of male participtants using cabergoline, a prolactin-lowering medication. The results were impressive in many cases:
1. Men with High Prolactin. Almost all the men in the study had their testosterone restored - high prolactin lowers T - and cabergoline not only restored their testosterone but usually their sexual function as well. [1]
2. Men with Psychogenic Erectile Dysfunction. Cabergoline helped in many key areas that us men are interested in. For example, it improved a) testosterone, b) erectile function, c) libido and d) orgasmic function. [2]
3. Decrease of Refractory Period. According to one animal study, lowering prolactin can decrease the refractory period, which is the time necessary for recuperation between orgasms. [3]
Now just in case you reading this and about to run out and order some from the nearest offshore pharmacy, I should point out that cabergoline is full of side effects. It would probably be a much more popular medication if this were not the case. Furthermore, it is one thing to have normal or slightly high prolactin levels and take cabergoline and still another to have low prolactin levels to start with. One cannot simply assume that low prolactin is always a good thing and any man with low prolactin levels would be a high testosterone, high libido bedroom machine. Unfortunately, this is not the case for reasons I will discuss below - quite the opposite actually. In fact, low prolactin is very often the sign of underlying medical conditions.
NOTE: Elevated prolactin can lower testosterone and, if high enough, lead to a type of secondary hypogonadism. For more information, see my page on Testosterone and Prolactin for more information.
The reason that low prolactin can so negatively affect your sex life was shown in a 2009 study in the Journal of Sexual Medicine that divided over 2,500 men with sexual dysfunction into quartiles and found that the low prolactin men were:
- 74% more likely to have Metabolic Syndrome
- 43% more likely to erectile dysfunction resulting from arterial disease and plaque
- 38% more likely to have premature ejaculation
Researchers are just getting their arms around the subject, but it appears that prolactin improves insulin release and "supports the growth of pancreatic islets", both of which will decrease risk for diabetes and prediabetes. [5] This probably also explains to the increased risk for arteriosclerosis and erectile dysfunction in the above study. Both diabetes and prediabetes are risk factors for heart disease and impotence.
NOTE: High prolactin has been shown in multiple studies to lead to heart disease as well. [6]
Why would low prolactin levels lead to premature ejaculation? As mentioned above, prolactin levels are very tied to one's post-intercourse recovery time: the higher the prolactin, the longer the recovery time. (Nitric oxide levels seem to also play a role.) And, apparently, low prolactin levels can lead to a very short recovery time and premature ejaculation as well. This condition can be very hard on relationships and increase anxiety and depression.
So what was the lowest quartile? It was prolactin levels below 113 mU/L or 5 ng/ml. For this reason, if you having any kind of erectile dysfunction or loss of libido and, if you also have low prolactin levels, this may provide you a clue as to how to troubleshoot the underlying issue.
NOTE: One animal study indicates that a zinc deficiency can lead to low prolactin levels, so you may want to get that checked. [8] Some men do a taste test for zinc testing. Be cautious, though, with raising levels too high as zinc may be neurotoxic and cause many other problems if one goes too high. See my page The Potential Dangers of Zinc for more information.
[h=1]Other Causes of Low Prolactin[/h]Low prolactin can in some cases be a sign of underlying medical disorders, which is why it's always important to work with a physician when you have low prolactin. Here are a few examples:
1) Hemachromatosis. This very common genetic disorder - about 1 out of 200 in men of European ancestry - can lead to hypogonadism as I document in my link on Causes of Low Testosterone. It turns out that it can also lead to hypoprolactinemia, or clinically low prolactin. As the iron builds up, hypothalmic function goes down and, of course, the hypothalamus controls many pituitary pathways. By the way, one obvious solution would seem to be just donate blood to reduce iron stores. Unfortunately, this may not work according to one study, which noted that "no significant improvement was noted, however, in growth hormone or prolactin secretion after phlebotomy. Of the 11 patients, 7 had secondary hypogonadism, and phlebotomy did not improve the serum testosterone, follicle-stimulating hormone, luteinizing hormone, or responses to LHRH in any case." [7]
2) Pituitary Disorders and Head Trauma. Of course, head injuries, tumors of the pituitary, tumors near the pituitary and other disorders can affect prolactin output. Discusss with an endocrinologist if you have any concerns.
3) Medications. Many medications can lower (or raise) prolactin levels and so you should consult with your physician if you are on medications and your prolactin is low. Check out this study for a sample of all the medications that can affect prolactin. Remember that anything that affects dopamine is likely to affect prolactin as well.
REFERENCES:
1) The Journal of Clinical Endocrinology & Metabolism February 1, 2004 vol. 89 no. 2 621-625, "Six Months of Treatment with Cabergoline Restores Sexual Potency in Hyperprolactinemic Males: An Open Longitudinal Study Monitoring Nocturnal Penile Tumescence"
2) International Journal of Impotence Research, 2007, 19:104–107, "Cabergoline treatment in men with psychogenic erectile dysfunction: a randomized, double-blind, placebo-controlled study"
3) Behav Brain Res, 1984 Jun, 12(3):267-73, "Brain monoaminergic control of male reproductive behavior. II. Dopamine and the post-ejaculatory refractory period"
4) J Sex Med, 2009 May, 6(5):1457-66, "Hypoprolactinemia: a new clinical syndrome in patients with sexual dysfunction"
5) Trends in Endocrinology & Metabolism, Apr 2006, 17(3):110-116, "Focus on prolactin as a metabolic hormone"
6) Hypertension, 2009, 54:98-105, "Prolactin and Preclinical Atherosclerosis in Menopausal Women With Cardiovascular Risk Factors"
7) Mayo Clinic Proceedings, Jun 1987, 62(6):473–479, "Influence of Phlebotomy Treatment on Abnormal Hypothalamic-Pituitary Function in Genetic Hemochromatosis"
8) Nahrung, 1989, 33(10):935-40, "Role of zinc in regulating the testicular function. Part 1. Effect of dietary zinc deficiency on serum levels of gonadotropins, prolactin and testosterone in male albino rats"
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