Just curious...what makes orals more liver toxic than say a Tylenol? Are orals more liver toxic than say...Tylenol? Is the only difference because you would not take a Yylenol everyday for 6 weeks, or is there something more? I wonder this because we probably all know of people (probobly older folks) that must take handfulls of medication daily. Thank you.
Oral Toxicity Question
- Thread starter OldNewbie
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It's the methylation of the oral steroids that make the, so liver toxic, and much more than Tylenol. They have a much more profound effect on the liver. Certain orals are also more toxic than others. For example Anadrol is pretty toxic compared to tbol, even though tbol is still very toxic. All of them will raise liver values quite a bit and that's the reason we always recommend a good liver support like TUDCA, NAC, milk thistle, liv 52, etc while on orals
How is liver damaged while running oral steroid cycle?
Liver is one of the most important organ in human as that if it shuts down we have only 2-3 days to live. It’s the “cleanser” of the body, helping to get rid of toxins. Fortunately for us, liver has the capacity to regenerate and be functional even when 75% of it is damaged.
All 17A oral steroids are modified in a way to avoid degradation in the liver and be able to get in the blood. These kinds of steroids are toxic to liver because they inhibit the excretory function of the liver. Likewise, liver can get rid of toxic and they accumulate in the body. Known as cholestasis this is the most common disease caused by 7aa oral steroids are blamed for.
If no action is taken then after a while this disease worsens and may turn into cirrhosis, a stage where the activity begins to slow down. Worth to be mentioned cholestasis is not a lethal disease and is reversible if needed measures are taken on time. The best is to avoid getting to this stage at all, as ideal is to keep your liver safe instead of trying to treat.
The things get worse when two 17A oral steroids are taken concomitantly. Never admit this mistake. Always try to cycle an oral steroid along with an injectable one, this being the smart way of using steroids.
Don’t put all oral steroids in the same light as not all of them are liver toxic. Some of them are more toxic than others, while a minority has no bad influence on liver at all.
Top most liver toxic oral steroids are:
Superdrol
Dymethazine
Halodrol
Epistane
DHEA
Epiandrosterone
The more potent is the steroid, the higher is the toxicity level it carries on. Therefore, avoid using a powerful oral steroid when looking for fast and impressive muscle gains.
Top of less liver toxic oral steroids:
Winstrol,
Dianabol,
Anadrol.
So, only 17-aa steroids are liver toxic, while all other steroid have minor to no influence at all. A good idea is to stack a 17aa steroid with a non one in order to keep your liver functional while enjoying noticeable gains in muscle mass.
Symptoms of a damaged liver
When your liver function is perturbed because of oral steroid use there are series of signs that you have to worry about. Pay a close attention to your overall feeling when running a steroid cycle to be able to prevent any disease before it will to late.
Here are some of signs that should alarm you when taking orals:
-Lowered appetite;
-Fever associated with nausea (many take it as a cold , but it is not);
-Itchiness;
-Yellowish skin or eyes;
Whenever one of these signs occurs is time to take a break and revise what you are doing wrong. The earlier you acknowledge what happens in your body and give a hand of help, the higher chances to pass through a cycle with your liver function untouched.
The best would be not to wait for these signs, but simply take enzymes before and after steroid cycle. Few weeks later after the cycle is finished repeat the tests and see how it shows. This way you will have a closer look on your liver situation.
anytime bro, im happy to help bro!
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