Is AAS oral toxicity more dosage or compound depending ?

[jlaix0]

By curiosity, I never really find a answer of this question...

Let's just take an exemple to be clearer:

"30mg of Dbol" vs "10mg Dbol with 25mg of Anadrol"

Is there a possibily (precise way) to know which one is more toxic ?

(even if I do know "toxicity" can both mean everything and nothing, but here it's just a small example to illustrate)

 

[Tazz]

30mg of dbol is more toxic than 10mg dbol and 25mg anavar .
it is dosage AND compound dependent.


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[44YOGearHead]

View attachment 2961

Var is actually broken down in the kidneys as it is actually used medically to treat involuntary weight loss caused by acute or chronic injury, illness and infection. So your kidneys are barely affected. First, 17a-methylated androgens/anabolics are all hepatotoxic. Liver injury due to oral AAS use typically occurs as cholestasis (blockage of bile ducts to your doudenum). Liver toxicity caused by oral AAS tends to be from the reduction, or stoppage of bile flow and increased serum levels of AST, ALT and GGT (elevated liver enzymes). When bile stops it tends to salt and this is highly cytotoxic (toxic to living cells) and leads to cellular level injury, apoptosis (cell death), then necrosis (rot and decay). This is followed by acute inflammatory reaction and tissue fibrosis (thickening and scarring of) the bile ducts. This damage can destroy your livers bile ducts, worsen and ultimately lead to sepsis and death. Remember, all oral steroids are hepatotoxic, this is why recommended dosages shouldn't be exceeded especially for an extended period of time.


TUDCA, Silymarin and Silybin are strong antioxidants and free-radical scavengers in liver tissue and should be taken with oral AAS along with copious amounts of water.


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[BigBusiness]

View attachment 2961

Var is actually broken down in the kidneys as it is actually used medically to treat involuntary weight loss caused by acute or chronic injury, illness and infection. So your kidneys are barely affected. First, 17a-methylated androgens/anabolics are all hepatotoxic. Liver injury due to oral AAS use typically occurs as cholestasis (blockage of bile ducts to your doudenum). Liver toxicity caused by oral AAS tends to be from the reduction, or stoppage of bile flow and increased serum levels of AST, ALT and GGT (elevated liver enzymes). When bile stops it tends to salt and this is highly cytotoxic (toxic to living cells) and leads to cellular level injury, apoptosis (cell death), then necrosis (rot and decay). This is followed by acute inflammatory reaction and tissue fibrosis (thickening and scarring of) the bile ducts. This damage can destroy your livers bile ducts, worsen and ultimately lead to sepsis and death. Remember, all oral steroids are hepatotoxic, this is why recommended dosages shouldn't be exceeded especially for an extended period of time.


TUDCA, Silymarin and Silybin are strong antioxidants and free-radical scavengers in liver tissue and should be taken with oral AAS along with copious amounts of water.


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hipocampus.me Board Rep and GAINZ Super Smart Mother fucker
Coupon Code: THE44
View attachment 2960

44 breaking it down. Take em to church!!

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[44YOGearHead]

I know right? I had a good post about Tren last night, now this? WTF... must be the Valhalla.

View attachment 2962

 

[RickRock]

By curiosity, I never really find a answer of this question...

Let's just take an exemple to be clearer:

"30mg of Dbol" vs "10mg Dbol with 25mg of Anadrol"

Is there a possibily (precise way) to know which one is more toxic ?

(even if I do know "toxicity" can both mean everything and nothing, but here it's just a small example to illustrate)

The short answer is both affect it. There's no clear cut answer. Certain compounds are more toxic than others, but depending on the situation a more toxic compound could be less toxic if it's low dosed compared to a higher dosed mild compound. The main thing to keep in mind is they are all toxic and should be treated as such. No doses should be abused, and if you ever run two orals they need to be ran at half normal doses


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[JackSteel]

It depends on both. I would pick one and do it optimally instead of trying to have your cake and eat it too with 10mg dbol. Yes I support low doses on AAS but when it comes to orals it's so quick and potent you may as well give yourself a swift kick in the pants with one.


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[DylanGemelli]

View attachment 2961

Var is actually broken down in the kidneys as it is actually used medically to treat involuntary weight loss caused by acute or chronic injury, illness and infection. So your kidneys are barely affected. First, 17a-methylated androgens/anabolics are all hepatotoxic. Liver injury due to oral AAS use typically occurs as cholestasis (blockage of bile ducts to your doudenum). Liver toxicity caused by oral AAS tends to be from the reduction, or stoppage of bile flow and increased serum levels of AST, ALT and GGT (elevated liver enzymes). When bile stops it tends to salt and this is highly cytotoxic (toxic to living cells) and leads to cellular level injury, apoptosis (cell death), then necrosis (rot and decay). This is followed by acute inflammatory reaction and tissue fibrosis (thickening and scarring of) the bile ducts. This damage can destroy your livers bile ducts, worsen and ultimately lead to sepsis and death. Remember, all oral steroids are hepatotoxic, this is why recommended dosages shouldn't be exceeded especially for an extended period of time.


TUDCA, Silymarin and Silybin are strong antioxidants and free-radical scavengers in liver tissue and should be taken with oral AAS along with copious amounts of water.


The 44
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Coupon Code: THE44
View attachment 2960

this post right here only justifies the fact that "smart motherfucker" is part of your signature... it only solidifies it! =) well said brother and honestly, not much more needs to be expounded upon as this covers it top to bottom... you already know how i feel on overuse of orals, stacking them etc... it has to be done with extreme precision, and consistency... using this is any sort of reckless manner is going to cause significant problems and you DO NOT want a completely recked blood panel... trust me, you dont want to deal with all of it as it can be extremely problematic and clearly makes it much harder to recover and maintain gains...

 

[44YOGearHead]

this post right here only justifies the fact that "smart motherfucker" is part of your signature... it only solidifies it! =) well said brother and honestly, not much more needs to be expounded upon as this covers it top to bottom... you already know how i feel on overuse of orals, stacking them etc... it has to be done with extreme precision, and consistency... using this is any sort of reckless manner is going to cause significant problems and you DO NOT want a completely recked blood panel... trust me, you dont want to deal with all of it as it can be extremely problematic and clearly makes it much harder to recover and maintain gains...

Thanks bro, I got a lot of time on my hands to read up on things and try to learn more... the actual application of things learned might need some brushing up on lol, but I plan on doing this a long time- kinda too far in to turn back (as if I really would), but learning is key. When I know something can do damage I wanna know how and why so I can avoid it rather than be the dumb ass in the firearms safety class holding the gun backwards and only getting off one round... to the face. Besides as a rep I feel you should know your shit and look the part, people depend on you for more than sales after all. Besides, between reading and watching all your vids I couldn't stay stupid forever lol.

 

[DylanGemelli]

Thanks bro, I got a lot of time on my hands to read up on things and try to learn more... the actual application of things learned might need some brushing up on lol, but I plan on doing this a long time- kinda too far in to turn back (as if I really would), but learning is key. When I know something can do damage I wanna know how and why so I can avoid it rather than be the dumb ass in the firearms safety class holding the gun backwards and only getting off one round... to the face. Besides as a rep I feel you should know your shit and look the part, people depend on you for more than sales after all. Besides, between reading and watching all your vids I couldn't stay stupid forever lol.

LOLLLL brother, you had plenty of knowledge already... if i added to that, then im thrilled to do so... your answers are always clear cut and precise and its appreciated by me and everyone here...